منابع مشابه
Rituximab: the Lupus Journey
Since the 1950s, lupus has changed from being a life-threatening condition to being treatable in most cases thanks to the introduction of steroids, immunosuppressive drugs, dialysis and renal transplantation. However, apart from the introduction of mycophenolate mofetil, successful new drugs for lupus have been hard to find in the past two decades. In an assessment of our lupus nephritis cohort...
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Like most benthic marine organisms, coral reef fishes produce larvae that traverse open ocean waters before settling and metamorphosing into juveniles. Where larvae are transported and how they survive is a central question in marine and fisheries ecology. While there is increasing success in modelling potential larval trajectories, our knowledge of the physical and biological processes contrib...
متن کاملPacking for the journey
Nearly 2 m of DNA is so tightly packaged that it fits neatly within the nucleus of each cell of our body. As if this was not mind-blowing enough, the problem is intensified in the male germline, as the nucleus of a sperm cell is about 6 times smaller than that of a somatic cell. Sperm are highly specialized cells charged with the sole responsibility of delivering the paternal genome to offsprin...
متن کاملThe Journey to smORFland
The genome sequences completed so far contain more than 20 000 genes with unknown function and no similarity to genes in other genomes. The origin and evolution of the orphan genes is an enigma. Here, we discuss the suggestion that some orphan genes may represent pseudogenes or short fragments of genes that were functional in the genome of a common ancestor. These may be the remains of unsucces...
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ژورنال
عنوان ژورنال: Canadian Theatre Review
سال: 2017
ISSN: 0315-0836,1920-941X
DOI: 10.3138/ctr.172.005